Connection between the East and the West

Alexander the Great and his Macedon generals had great impact in the development and extension of the Silk Road network of routes. Their campaigns are thought to be the first major step in opening the big connection between the East and the West. Alexander's empire extended from Greece to Central Asia. In Fergana Valley, which is located in modern Tajikistan, he founded the famous city Alexandria Eschate which later became the major point of northern Silk Road.

After his death Alexander's general Ptolemy and his descendants got Egypt and became first Greek pharaohs. Egypt heavily depended on trade, it had large sea ports on Red Sea and established routes to the Middle East and India and to the South, reaching East Africa.

As for Greek kingdoms in Central Asia, they lasted for the next three hundred years. They were trying to continue the expansion to Sogdiana and India and set up new Greco-Indian kingdoms there. Ancient historians noted not once that Greek kingdoms led their expeditions to China and Chinese Turkestan around 200 BC, which constitutes the first verified by documents contact between China and the West.